"Power and sample size estimations are measures of how many patients are needed in a study. Nearly all clinical studies entail studying a sample of patients with a particular characteristic rather than the whole population. We then use this sample to draw inferences about the whole population."
Reference: Jones SR, Carley S, Harrison Man introduction to power and sample size estimation. Emergency Medicine Journal 2003;20:453-458.
The references in this section will help you calculate what is a minimum adequate sample for your study to draw valid conclusions.
1. Jones SR, Carley S, Harrison M. An introduction to power and sample size estimation. Emergency Medicine Journal 2003;20:453-458. https://emj.bmj.com/content/20/5/453 (FREE)
2. Online sample size calculator for clinical research: https://www.openepi.com/Menu/OE_Menu.htm
3. Suen LJ, Huang HM, Lee HH. [A comparison of convenience sampling and purposive sampling]. Hu Li Za Zhi. 2014 Jun;61(3):105-11. Chinese. doi: 10.6224/JN.61.3.105. PMID: 24899564. https://pubmed.ncbi.nlm.nih.gov/24899564/
4. Guerra Valero YC, Wallis SC, Lipman J, Stove C, Roberts JA, Parker SL. Clinical application of microsampling versus conventional sampling techniques in the quantitative bioanalysis of antibiotics: a systematic review. Bioanalysis. 2018 Mar;10(6):407-423. doi: 10.4155/bio-2017-0269. Epub 2018 Feb 16. PMID: 29451394. https://pubmed.ncbi.nlm.nih.gov/29451394/
5. Tanna S, Lawson G. Self-sampling and quantitative analysis of DBS: can it shift the balance in over-burdened healthcare systems? Bioanalysis. 2015;7(16):1963-6. doi: 10.4155/bio.15.110. PMID: 26327176. https://pubmed.ncbi.nlm.nih.gov/26327176/
6. Li H, Han J, Pan J, Liu T, Parker CE, Borchers CH. Current trends in quantitative proteomics - an update. J Mass Spectrom. 2017 May;52(5):319-341. doi: 10.1002/jms.3932. PMID: 28418607. https://pubmed.ncbi.nlm.nih.gov/28418607/
7. Trevelin LC, Novaes RL, Colas-Rosas PF, Benathar TC, Peres CA. Enhancing sampling design in mist-net bat surveys by accounting for sample size optimization. PLoS One. 2017 Mar 23;12(3):e0174067. doi: 10.1371/journal.pone.0174067. PMID: 28334046; PMCID: PMC5363843. https://pubmed.ncbi.nlm.nih.gov/28334046/